Iran launched another nighttime missile barrage of 5 projectiles toward central Israel, all intercepted with debris causing a building fire in Holon. Israel immediately retaliated by striking Tehran, Isfahan, and eliminating three Revolutionary Guard commanders, including Said Izadi who coordinated Hamas funding. A widespread Iranian drone attack followed in the morning, with one achieving the first direct hit on an Israeli residential building in Beit Shean since the war began, though no casualties occurred. Israeli strikes significantly damaged centrifuges at Isfahan's nuclear facility. Media reported Khamenei designated three successors fearing assassination, while six American B-2 bombers deployed to Guam carrying bunker-penetrating bombs capable of striking Iran's underground Fordo facility. The day concluded with diplomatic tension as Israel informed the Trump administration it would not wait two weeks for his decision and threatened to strike Fordo independently. Vice President Vance reportedly expressed anger during tense phone calls, accusing Israel of "dragging America into war."